old Guava leaf actually contain assortedly [of] the component berkhasiat to overcome disease of dengue dengue ( DBD). Group Compound tanin and flavonoid expressed as quersetin in guava leaf extract can pursue the enzyme activity reverse trancriptase meaning to pursue growth of virus of core of RNA.
That way the result of research done by Badan Pengawas Obat and Makanan (POM) cooperate with Faculty of mediciness and Faculty of pharmacy Universitas Airlangga ( Unair) Surabaya, which since 2003 checking the guava leaf extract for medication DBD. [At] research early stage started with examination preklinik. Result of research dipaparkan by Kepala Badan POM Drs Sampurno MBA in Jakarta, Wednesday ( 10/3).
Research idea come from Badan POM and they refer Dr Drs Suprapto Ma’at MS. apothecary from Patologi FK Unair to check the guava leaf.
Be like known, DBD is the disease because of virus dengue with mortality and high enough painfulness. Till now medication DBD still have the character of suportif, that is overcoming plasma dilution loss effect of improvement of capillary venous permeability.
[At] early stage done by theX the research preklinik in FK Unair using the animal model mencit with [gift/ giving] oral proven guava leaf extract can downhill [of] venous permeability. [At] the research is reported also that proven guava leaf extract can improve the cells amount hemopoetik especially megakriosit [at] preparat and bone marrow culture mencit. [At] security test ( toksisitas) guava leaf extract including practical Iihat vitamin not toxic.
Pursue the virus dengue
Guava leaf is truely contain assortedly [of] component. Relate to that have been done by theX the test invitro guava leaf extract where do the extract proven can pursue growth of virus dengue. Later after done by theX the research is furthermore expected by theX the guava leaf extract serve the purpose of medicinize anti virus dengue.
Have also been done by theX the test early in the form of research open lable in some hospitals in East Java ( RS JOMBANG and RS Petrokimia Gresik) [at] patient DBD adult and children.
“ Research result distributed to RS Jombang in the form of 30 capsule and 30 syrup, then RS Petrokimia Gresik 20 capsule and 20 syrup. There is voluntary which will try,” word Suprapto.
the Research result indicate that [gift/ giving] of guava leaf extract can quicken improvement of trombosites amount without accompanied by theX the side effects mean, for example constipation. Research open this lable still needed to continue with clinic test to prove khasiat with evidence based the strongerness.
Other perception is in process in this research is influence of [gift/ giving] of guava leaf extract to sekresi GM-CSF and IL-11 to know his [job/activity] mechanism [at] trombopoiesis. Also to complement system activity and sekresi TNF-Alfa olehmonosit in his [relation/link] with mechanism degradation of venous permeability.
In the year 2004 will be done by theX the clinic test in RSUD Dr Soetomo Surabaya/FK Unair, to be led by Prof Dr dr Sugeng Sugijanto DSA assisted dr M Nasirudin with Dr Ugrasena for patient DBD child and Prof dr Edy Soewandojo SpPD for patient DBD adult.
Body POM during near also will do the intensive studies with expert to support the present managery exist. Sampurno optimism because its raw material guava leaf is very easy go and simple him technology process. (LOK)